Chronic Wasting Disease Agents in Nonhuman Primates
نویسندگان
چکیده
Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
منابع مشابه
Interspecies transmission of chronic wasting disease prions to squirrel monkeys (Saimiri sciureus).
Chronic wasting disease (CWD) is an emerging prion disease of deer and elk. The risk of CWD transmission to humans following exposure to CWD-infected tissues is unknown. To assess the susceptibility of nonhuman primates to CWD, two squirrel monkeys were inoculated with brain tissue from a CWD-infected mule deer. The CWD-inoculated squirrel monkeys developed a progressive neurodegenerative disea...
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عنوان ژورنال:
دوره 20 شماره
صفحات -
تاریخ انتشار 2014